Protective effect of renal ischemic postconditioning in renal ischemic-reperfusion injury
نویسندگان
چکیده
منابع مشابه
Protective effect of ischemic postconditioning against hepatic ischemic reperfusion injury in rat liver
PURPOSE The efficiency of ischemic postconditioning (IPC) was evaluated in a rat model of ischemic liver. Concentration of survivin of liver tissue correlated with the degree of antiapoptosis, so survivin was estimated to evaluate the efficiency of IPC on ischemic reperfusion (IR) injury. METHODS Twenty-four healthy rats were divided to three groups (SHAM, IR, and IPC). Rats in the SHAM group...
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Background and aim: Acute kidney injury (AKI) is a frequent complication of kidney failure with high mortality which leads to brain dysfunction. The aim of this study was to investigate the possible protective effect of ischemic postconditioning (IPo) against brain dysfunction induced by bilateral renal ischemia (BRI). Materials and methods: Male Wistar rats underwent BRI, sham or IPo surgery ...
متن کاملEvaluating the effect of short ischemic periods on subsequent rat renal ischemic injury
Introduction: Using brief episodes of ischemia and reperfusion (IR) prior to a more sustained IR insult – ischemic preconditioning (IPC) – can reduce IR injury of the heart, brain and many other tissues. The purpose of present study was to investigate the effect of 2min ischemic periods on subsequent rat renal IR injury. Methods: Male rat's renal IR injury was investigated in a right nephrectom...
متن کاملProtection of Liver as a Remote Organ after Renal Ischemia-Reperfusion Injury by Renal Ischemic Postconditioning
This study was designed to investigate the protective effects of local renal ischemic postconditioning (POC) on liver damage after renal ischemia-reperfusion (IR) injury. Male rats were divided into three groups (n = 8). They underwent a right nephrectomy before induction of 45 minutes of left kidney ischemia or sham operation. POC was performed by four cycles of 10 seconds of ischemia and 10 ...
متن کاملIschemic postconditioning prevents renal ischemia reperfusion injury through the induction of heat shock proteins in rats
Ischemic postconditioning (IPo) attenuates ischemia‑reperfusion injuries (IRI) in various organs, of both animals and humans. This study tested the hypothesis that IPo attenuates renal IRI through the upregulation of heat shock protein (HSP)70, HSP27 and heme oxygenase‑1 (HO‑1, also known as HSP 32) expression. Adult Sprague Dawley rats were subjected to bilateral renal ischemia for 45 min foll...
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ژورنال
عنوان ژورنال: Translational Andrology and Urology
سال: 2020
ISSN: 2223-4683,2223-4691
DOI: 10.21037/tau-20-859